Alexander and Ann Shulgin are personal explorers in the use of psychedelics. According to Nicholas Saunders they follow up their renowned book, "Pihkal" with a book that, "not only reveals how psychoactives can be synthesised, but also how they can be extracted from so many ordinary plants that the means for psychedelic exploration can never be controlled again. The genie is out of the bottle and all the king's horses and all the king's men cannot put it back again."